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The method for measuring the sensitivity of the bottleneck degree to the bottleneck shifting factors was proposed. According to the material-flow bottleneck defining, the production capability and load were described from the perspectives of process speed and quality level, then the bottleneck index was constructed to characterize the degree of manufacturing unit blocking the material-flow (that is bottleneck degree). Based on the measurement of the sensitivity of the bottleneck index to the single bottleneck shifting factor and DEMATEL method for analyzing the relationship of the factors, bottleneck shifting sensitivity index was built to measure the sensitive degree of bottleneck index to the uncertain environment. At the end of this thesis, an example for monitoring the bottleneck and measuring sensitive degree to the uncertain environment in job shop was given to prove the validation and practicability of bottleneck index and bottleneck shifting sensitivity index.